More than 15 years of experience
Stress your formulation,
not yourself
Physiolution GmbH was founded by Prof. Dr. Werner Weitschies and Dr. Grzegorz Garbacz as a spin-off of the University of Greifswald in November 2009. Physiolution GmbH is a highly innovative company focused on investigations of the dissolution behaviour of solid oral dosage forms under bio-relevant test conditions. The cutting edge test methods utilized by Physiolution GmbH were established by the founders and are based on long experience in the fields of gastro-intestinal tract physiology and biopharmaceutical evaluation of dosage form performance. The bio-relevant test devices realistically simulate the mechanistic and physico-chemical conditions that act on dosage forms during their gastro-intestinal passage and enable the evaluation of their biopharmaceutical safety and reliability. The applicability of the test devices and test procedures was successfully validated on numerous examples of clinical relevance as well as in the routine analyses of solid oral dosage forms. In addition, the analytical services of Physiolution GmbH include pharmacopoeial dissolution testing and other pharmacopoeial investigations of solid oral dosage forms and their mechanical stability as well as development and validation of analytical methods and procedures.
Bio-predictive dissolution testing
Bio-predictive dissolution testing
Analysis of the therapeutic target with particular emphasis on the influence of gastrointestinal physiology and dosing schedule
Preclinical characterization
Preclinical characterization
Preclinical evaluation of solid oral drug formulations including anticancer, neuroleptic and potent drugs
Quality Product
Quality Product
Our products are facing all aspects of physiologic variability - Regulation of highly dynamic gastro-intestinal pH gradients - Stress Testing
Formulation of biomolecules and analytical support of product development
Analytical support of product development
Interpretation of pharmacokinetic studies and physiological mechanisms affecting dissolution characteristics of oral drugs
Why Choose Us
We Provide World Class
IT Solution Service
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